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Post by tiffbabey on Jul 20, 2017 17:33:27 GMT -6
So I had my first appointment today, and I am a little confused about the genetic testing. They do offer the cell free DNA testing, the harmony, I think, but she said that low risk pregnancies don't have a very accurate outcome, a lot of false positives. And if there was a false positive then next step would be a more invasive test. We are very low risk and I am only 30, but with my son they found a focus on his heart and we ended up doing the test at 21 weeks. We're not that concerned but obviously a huge benefit would be finding out the sex early.
Anyone low risk still do the test even with the chance of false positives?
Anyone have Tufts HMO and know how much it would cost?
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Post by rebeccabunch on Jul 20, 2017 18:44:27 GMT -6
I've never had it explained to me that way with the false positives but I don't know how the Harmony Test differs from the Counsyl test I did.
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Post by flippinchica on Jul 20, 2017 18:54:27 GMT -6
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pippiann
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Post by pippiann on Jul 20, 2017 22:58:48 GMT -6
I didn't read the article but my genetic counselor also said that the chances are higher for false positives in traditional testing than the DNA testing, actually chances were a lot lower. Sent from my iPhone using Tapatalk
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Post by helloerrbody on Jul 21, 2017 7:47:18 GMT -6
I am low-risk and did the testing, because I want to know the sex now. The test my midwife uses maxes at $80 OOP regardless of what my insurance covers so it wasn't a huge cost (cheaper than an elective u/s).
My midwife says false positives are of course possible but she rarely rarely sees them. If we receive a positive on anything, we will 100% not be doing an amniocentesis or CVS. We will just be educating ourselves, praying, and waiting to see what the a/s shows. And hoping it's a false positive of course but preparing our hearts and minds either way.
Good luck with your decision!
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Post by hiimjamie on Jul 21, 2017 9:10:49 GMT -6
I've never heard of that. I'm low risk and 31. My doc only does the free cell DNA testing if you're older or higher risk but they did offer Sequential Screening to me, which we did. I guess it tests proteins instead of looking at the chromosomes. You can't find out the sex (womp) but everything came back normal for us.
Sent from my iPhone using Tapatalk
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Post by rebeccabunch on Jul 21, 2017 10:57:16 GMT -6
I am low-risk and did the testing, because I want to know the sex now. The test my midwife uses maxes at $80 OOP regardless of what my insurance covers so it wasn't a huge cost (cheaper than an elective u/s). My midwife says false positives are of course possible but she rarely rarely sees them. If we receive a positive on anything, we will 100% not be doing an amniocentesis or CVS. We will just be educating ourselves, praying, and waiting to see what the a/s shows. And hoping it's a false positive of course but preparing our hearts and minds either way. Good luck with your decision! Did you find out the sex yet and I missed it?
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Post by blueskiessmiling on Jul 21, 2017 11:47:42 GMT -6
I did the cell-free DNA testing. My OB only does this kind of testing now (vs offering the quad screening). She said it's much more accurate and also screens for things that the quad screening doesn't. I'm low risk, but didn't have any issues with false positives- mine came back all negative.
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aprilz81
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Post by aprilz81 on Jul 21, 2017 15:13:48 GMT -6
I'm not a scientist, but I don't understand how being low risk can result in MORE false positives.
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Post by helloerrbody on Jul 21, 2017 18:56:54 GMT -6
I am low-risk and did the testing, because I want to know the sex now. The test my midwife uses maxes at $80 OOP regardless of what my insurance covers so it wasn't a huge cost (cheaper than an elective u/s). My midwife says false positives are of course possible but she rarely rarely sees them. If we receive a positive on anything, we will 100% not be doing an amniocentesis or CVS. We will just be educating ourselves, praying, and waiting to see what the a/s shows. And hoping it's a false positive of course but preparing our hearts and minds either way. Good luck with your decision! Did you find out the sex yet and I missed it? No don't worry I'll AW the shit outta it when I do lol. Should get results back late next week. For whatever reason the company my midwife's office uses takes up to 3 weeks to get back. 😑
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Post by helloerrbody on Jul 21, 2017 18:57:18 GMT -6
I'm not a scientist, but I don't understand how being low risk can result in MORE false positives. Doesn't make sense to me either. 🤷🏼♀️
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Post by flippinchica on Jul 22, 2017 0:04:55 GMT -6
I'm not a scientist, but I don't understand how being low risk can result in MORE false positives. Doesn't make sense to me either. 🤷🏼♀️ Definitely geeky statistics stuff but Basically if the prevalence of a condition is high a positive result is more likely to represent a true positive (actually be affected) and is the prevalence is low in a population (low risk) a positive is more likely to be a false positive. That being said genetic testing is an extremely accurate screening. Anecdotally I have seen a lot of false positive results on the boards with traditional screening but never seen one with cell free DNA testing. One person got a no result and then on another brand was positive for trisomy 21 confirmed by amnio. And I remember one poster for whom the sex was wrong.
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Post by ldubhawksfan on Jul 24, 2017 15:58:35 GMT -6
D17 lurker but thought I would chime in. My dr didn't tell me about low risk/high rate of false positives, so I opted for the state quad screening like I did with DD. 1st tri results fine. 2nd tri results came back abnormal with 1:30 risk of Down's syndrome. I then got routed to a genetic counselor and we did the other, more precise, blood work (genetic testing) to find out what the results were before going on to an amnio. I just heard back today that the results are negative and the baby is fine. So the last 2 weeks I've had extra stress and worry. I guess we were a false positive. Knowing what I know now, I don't know if we would have opted to pay OOP for the genetic testing, but I suppose it would have saved me that extra worry.
Ask your dr office what the cost would be if not covered by insurance. Good luck!
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