Humira and BF
Apr 19, 2018 7:38:31 GMT -6
Post by jt2378 on Apr 19, 2018 7:38:31 GMT -6
Hello Ladies! I hope you don't mind me popping in to get some of your wise opinions.
My DD is 8 months old and I have recently been diagnosed with Crohns which unfortunately just came out of nowhere at 37 weeks pregnant last summer. Now I'm at the point that I need to make some treatment decisions and the recommended option is Humira. Initially I thought no way would I take it with BF even though my GI doctor said it actually isn't unsafe and women do. After doing my own research, there actually is data supporting that claim that I found on Infant Med Risk.
It says: "By no means stop breastfeeding. We do have some data on Humira which suggests its transfer into human milk is very low with a relative infant dose of only 0.12%. This is exceedingly low. Even this amount present in the babies gut, would be largely metabolized like any other protein, and not really absorbed systemically to any degree. Studies in two infants suggested levels in milk were negligible and of no consequence."
This was another post but regarding a 15 month old: ---What would happen if any Humira was absorbed by the baby?
I doubt anything would happen if small amounts were absorbed. The dose would simply be too low to produce any complications. At the very worst, he might have a higher risk of infection in the gut. But again this is so unlikely its not worth worrying about.
---Are there any recommended strategies for maximizing safety if you do breastfeed while on Humira? No. at 15 months the amount of milk you produce is low. I wouldn't worry about it.
---Given my child is older (and so breast milk is not his only source of food), do the risks outweigh the benefits of breastfeeding? The risks are nil. Benefits far outweigh any risk.
Does anyone have experience with this? Anecdotes, opinions, thoughts? Thanks so much for taking the time to read and any insight you can provide.
My DD is 8 months old and I have recently been diagnosed with Crohns which unfortunately just came out of nowhere at 37 weeks pregnant last summer. Now I'm at the point that I need to make some treatment decisions and the recommended option is Humira. Initially I thought no way would I take it with BF even though my GI doctor said it actually isn't unsafe and women do. After doing my own research, there actually is data supporting that claim that I found on Infant Med Risk.
It says: "By no means stop breastfeeding. We do have some data on Humira which suggests its transfer into human milk is very low with a relative infant dose of only 0.12%. This is exceedingly low. Even this amount present in the babies gut, would be largely metabolized like any other protein, and not really absorbed systemically to any degree. Studies in two infants suggested levels in milk were negligible and of no consequence."
This was another post but regarding a 15 month old: ---What would happen if any Humira was absorbed by the baby?
I doubt anything would happen if small amounts were absorbed. The dose would simply be too low to produce any complications. At the very worst, he might have a higher risk of infection in the gut. But again this is so unlikely its not worth worrying about.
---Are there any recommended strategies for maximizing safety if you do breastfeed while on Humira? No. at 15 months the amount of milk you produce is low. I wouldn't worry about it.
---Given my child is older (and so breast milk is not his only source of food), do the risks outweigh the benefits of breastfeeding? The risks are nil. Benefits far outweigh any risk.
Does anyone have experience with this? Anecdotes, opinions, thoughts? Thanks so much for taking the time to read and any insight you can provide.
